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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2512 - 21 February 2020 Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M65. Flank. Slowly growing firm nodular mass
(c/o Dr. Florence Deroide & Dr. George Meligonis)


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Krishnakumar subramanian

Posted

other possibility is degenerating schwanomma

can we have CD34 IHC

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SFT is usually diffusely and strongly positive, whereas PHAT is focally or partially positive...but I favor PHAT. The truly morphologic differential, in my opinion, is ancient schwannoma...but CD34 positivity is usually focal and in Antoni B areas.

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Krishnakumar subramanian

Posted

if CD 34 is positive it is PHAT first

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Dr. Richard Carr

Posted

This is a solitary fibrous tumour (STAT6+ve). I have not knowly seen a case present in the skin and I'm very grateful to Florence & George for kindly giving me sections from their case. My notes as follows:

DDx: PHAT, Solitary fibrous tumour
STAT6 +ve (99% of SFT)
Final Dx: Solitary fibrous tumour (STAT6+ve)
Primary cutaneous = rare
DDx Spindle cell lipoma, DFSP
WHO since 2013: Haemangiopericytoma = SFT

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