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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2479 - 6 January 2020 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M, 79 Right cheek, incisional biopsy. Ulcerated, nodule right cheek


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Dr. Mona Abdel-Halim

Posted

Favor one of the aggressive cytotoxic TCLs either: extranodal NK-TCL or gamma-delta TCL. Will ask for CD3, CD5, CD7, CD4, CD8, CD30, TIA, Granzyme, CD56, TCRgamma, EBER.

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Krishnakumar subramanian

Posted

anglocentric atypical lymphoid lesions

agreed we need the markers

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First hypothesis: extranodal (and extranasal) NK-T cell lymphoma. CD56 and EBER are of great help. Second hypothesis: infectious disease. I would perform Grocott stain and look for leishmania as well.

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I don't know what kind of lymphoma this is, without IHC. CD56+/EBER+ Ly is a nice suggestion. 

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Admin_Dermpath

Posted

Dr Chaudhry - all too clever and caught out !! Herpes infection 

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