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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2485 - 14 January 2020 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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35 year old male with lesion on right upper thigh


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Eman El-Nabarawy

Posted (edited)

Aneurysmal fibrous Histiocytoma associated with squamous epithelial-lined cysts.

Edited by Eman El-Nabarawy

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Dr. Mona Abdel-Halim

Posted

Aneurysmal FH with unusual cystic structures, some are lined by squamous epithelium and some has lining that looks cuboidal similar to hidrocystoma. Interesting lesion!.

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Krishnakumar subramanian

Posted

Aneurysmal FH with lot of vascular spaces lined with endothelial cells 

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Uma Sundram

Posted

Aneurysmal fibrous histiocytoma. Similar lesions with associated apocrine glands have been described in the literature as 'adenodermatofibroma'.

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I've signed out a similar case a couple of weeks ago. The lesion was big because of the cystic component, what raised clinical suspicion for malignancy. In addition, there was a focal micropapillary hyperplasia, as often seen in hydrocystomas. 

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Nabil Mansouri2

Posted

Thanks Dr Uma Sundran aneurysmal fibrous histicytoma is a good diagnosis. What about angiomatoid fibrous histicytoma since there is an endothelial lining ???? 

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