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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2609 - 07 July 2020 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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35 year old female with new lesion, left upper eyelid.


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Meenakshi Batrani

Posted

Seems like full thickness dysplasia- squamous cell carcinoma in situ. Sebaceous differentiation not apparent, but because of location sebaceous carcinoma in situ also to be considered. 

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vincenzo

Posted

Exophytic growth of papillary, well differentiated, acanthotic nonkeratinized transitional/squamous cells, with some goblet cells. I see  prominent, branching fibrovascular cores, with some hobnail hemangioma-like appearance, probably reactive. Favor Conjunctival Papilloma. 

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Richard Logan

Posted

I think this is a warty lesion of Bowen's disease.

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Richard Logan

Posted

Just noticed the age of the patient which makes ordinary Bowen's disease unlikely.  Perhaps this is HPV induced, but an unusual site.

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Uma Sundram

Posted

Conjunctival papilloma. I agree that some atypia is present, and the degree of atypia is definitely debatable. You may note that while the cells are hyperchromatic, they are well organized. Age of patient makes irritation related reactive papilloma more likely than SCCIS.

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