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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case: 2525 - 11 March 2020 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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45 year-old female with a 2 week history of “eruption.” This biopsy is from the left thigh.


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Dermatomyositis/LES. Favor DM because of plentiful dermal mucin and relatively poor interface damage. 

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Dr. Mona Abdel-Halim

Posted

Yes, it is the morphological picture of LE or dermatomyositis

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Victor Delgado

Posted

there is orthokeratosis, epidermal atrophy, vacuolar degeneration over the basal stratum with a few necrotic keratinocytes, there are interstitial edema with a bluish material between the collagen bundles, superficial and deep chronic inflamatory infiltrate with extention to the follicule, which shows the same changes as the epidermis. So, to me is good enough for connective tissue disease, favour DLE over Dermatomyositis

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Eman El-Nabarawy

Posted

Yes LE/DM for clinical and serological correlation.

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Yousra

Posted (edited)

Epidermal atrophy, vac degeneration, dermal mucin, superficial and deep infiltrate, good enough for CT diseases, but why are there many extravaated RBCs?

Edited by Yousra

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