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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case: 2525 - 11 March 2020 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
45 year-old female with a 2 week history of “eruption.” This biopsy is from the left thigh.
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Go to records March 2020

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vincenzo

Dermatomyositis/LES. Favor DM because of plentiful dermal mucin and relatively poor interface damage. 

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Yes, it is the morphological picture of LE or dermatomyositis

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Victor Delgado

Victor Delgado 6

Posted

there is orthokeratosis, epidermal atrophy, vacuolar degeneration over the basal stratum with a few necrotic keratinocytes, there are interstitial edema with a bluish material between the collagen bundles, superficial and deep chronic inflamatory infiltrate with extention to the follicule, which shows the same changes as the epidermis. So, to me is good enough for connective tissue disease, favour DLE over Dermatomyositis

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Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Yes LE/DM for clinical and serological correlation.

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Yousra

Yousra 0

Posted (edited)

Epidermal atrophy, vac degeneration, dermal mucin, superficial and deep infiltrate, good enough for CT diseases, but why are there many extravaated RBCs?

Edited by Yousra

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