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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2568 - 11 May 2020 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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77M, Left cheek, Punch biopsy. Several months non-healing lesion. E/o Firm nodule under skin. ?Cyst. ?Atypical SCC.


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Nivedita

Posted

The expression of melanocytes markers HMB45is reduced and they express S100 and SOX10

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vincenzo

Posted

Melanoma ( spindle cell type ).

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Yes. I agree with melanoma. I could appreciate some intranuclear cytoplasmic protrusion that would be a clue for melanocytic differentiation.

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Meenakshi Batrani

Posted

I am also thinking of spindle cell melanoma

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Dr. Mona Abdel-Halim

Posted

Spindle cell melanoma

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Krishnakumar subramanian

Posted

can we have CD34 

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Admin_Dermpath

Posted

Dr. Chaudhry final comment on the case - please see below;
 

Thank you for your diagnoses. The features are those of a spindle cell melanoma.

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