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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2673 - 05 October 2020 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M55, Nodules and plaques on the scalp and face with follicular prominence and loss of hair of gradual onset and progressive course since 4 years.


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Folliculotropic Mycosis Fungoides. 

LyP type B or type D doesn’t fit well the clinical history. 

Primary Cutaneous CD8+ Aggressive Epidermotropic T-cell Lymphoma is usually an acute or subacute aggressive disease, instead this one seems something chronic progressive, as expected in FMF. 

CD3, CD2, CD5, CD7, CD4, CD8?

CD30, TIA1, CD45RA, CD45RO?

 

 

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Richard Logan

Posted

Agree with folliculotropic CTCL.  Sebaceous glands have been completely destroyed.  With the eye of faith there is some mucin hanging around where the sebaceous glands would have been, so you might also include CTCL-associated follicular mucinosis in the description.

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Meenakshi Batrani

Posted

Agree with folliculotropic MF

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Krishnakumar subramanian

Posted

 folliculotropic MF with mucinous changes

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Dr. Mona Abdel-Halim

Posted

Yes, folliculotropic MF

cells were CD3+, CD20-, CD4 predominated over CD8 and CD7 showed marked loss. 

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