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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2689 - 27 October 2020 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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92 year old female with lower lip lesion.


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Richard Logan

Posted

A hyperplastic keratosis showing Bowenoid dysplasia with prominent dyskeratosis, acantholysis and a lichenoid reaction.  Early invasion cannot be excluded on this specimen.

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Krishnakumar subramanian

Posted

Lichen planus turning to Dysplasia

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Many years ago I would have called this “lichenoid dysplasia”...

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Victor Delgado

Posted

Hello everyone, very difficult case, I'm looking forward to know the final diagnosis and what could teach us @Uma Sundram about this entity.

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Actinic keratosis with incidental acantholytic dyskeratosis.

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Uma Sundram

Posted

Apologies for the delay in response. Seems to be a habit these days! Sorry, guys. Am chalking it up to Covid 19! Anyway, a difficult case. We did end up saying, we favored reactive but it's a partial biopsy. If clinical concern persists, to re biopsy after treatment. Interesting that most people here thought it was dysplastic. I like sharing these ambiguous cases with you, to see what other people would do.

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Dr. Richard Carr

Posted

Agree looks dysplastic. I'd do Ki67, p16, p53.

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