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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2802- 2 April 2021 Posted By: Dr. Richard Carr

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F30. Anterior hairline. Previously biopsied, thought to be viral wart, recurred. Immunosuppressed SLE. ?SCC/viral wart.

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This is a challenge. It seems something of follicular differentiation: infundibular hypergranular growth and germinal trychoblastic with pmb stromal partner, and trichilemmal features, but don’t see any matrichal differentiation. Not enough to think of panfolliculoma?

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Meenakshi Batrani

Posted (edited)

Benign follicular tumor. Some resemblance to PIlar sheath acanthoma but also shows papillary mesenchymal bodies and abortive bulb- may be an unusual panfolliculoma. 

Edited by Meenakshi Batrani

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Dr. Richard Carr


Yes I agree. This was a benign follicular tumour that had not read the textbooks in any detail. Pilar sheath acanthoma-like and could be classified as a variant of panfolliculoma or even trichoblastoma. The p16 and p53 lacked aberrant patterns. You could debate if there were HPV-associated changes but that would need some in situ technique to confirm.

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