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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2816- 22 April 2021 Posted By: Saleem Taibjee

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Excision elderly man (site not stated)


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Richard Logan

Posted

I think this may be another example from Saleem of BCC with neuroendocrine differentiation. 

I am assuming that the "elderly man" was not excised, only a small part of him!

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vincenzo

Posted

DTE-like Basal Cell Carcinoma. CD10/BerEp4?

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Meenakshi Batrani

Posted

Infiltrative BCC. There seems to be area of neuroendocrine differentiation. 

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Saleem Taibjee

Posted

I think my mission is partly accomplished! At least 2 people are now readily identifying BCCs with neuroendocrine differentiation which are not uncommon. The immunostains are fully compatible (BerEP4 positive, EMA negative, CK20 negative, chromogranin and synaptophysin positive). Unfortunately there is a glitch, and I can't upload the images. I'll ask the DermpathPro team if they can do this.

BW Saleem

 

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vincenzo

Posted

Nice case, Saleem, and good job to Richard and Meenakshy. 

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