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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2817- 23 April 2021 Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical details: F70. Eyelid. Cyst of Moll burst on removal.


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? Endocrine Mucin Producing Sweat Glands Carcinoma. 

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Richard Logan

Posted

Yes I agree.  The cytology in this case is identical to that shown in case 2601, posted 25th June 2020.

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daniellindsay

Posted

Should synaptophysin be positive for this diagnosis?

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Dr. Richard Carr

Posted

Brilliant responses. Agree this was a nice case of EMPSGC. Easily mis-diagnosed if you are not aware of the features. As you can see neuroendorcine markers including synaptophysin can be quite variable, focal and weak as in this case. I thought this lesion was "in-situ" / intra-cystic. I cannot remember if it was re-excised (I'm on hols but will check on my return).

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Dr. Richard Carr

Posted

Sorry I don't have any follow-up in my database.

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