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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2890 - 04 August 2021 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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59-year-old female with biopsy of vulvar lesion.


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Eman El-Nabarawy

Posted

Benign solitary keratosis with hypergranulotic dyscornification.

The most distinctive histopathologic finding is the presence of a prominent granular layer with clumped perinuclear keratohyaline granules. Some cases had mounds of rounded, anucleate glassy eosinophilic corneocytes in the stratum corneum. 

https://pubmed.ncbi.nlm.nih.gov/31157457/

 

DD: Epidermolytic acanthoma.

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Meenakshi Batrani

Posted

Agree with epidermolytic acanthoma

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vincenzo

Posted

Epidermolytic Acanthoma. 

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Dr. Hafeez Diwan

Posted

Epidermolytic acanthoma

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volha

Posted

On 04/08/2021 at 13:09, Eman El-Nabarawy said:

Benign solitary keratosis with hypergranulotic dyscornification.

The most distinctive histopathologic finding is the presence of a prominent granular layer with clumped perinuclear keratohyaline granules. Some cases had mounds of rounded, anucleate glassy eosinophilic corneocytes in the stratum corneum. 

https://pubmed.ncbi.nlm.nih.gov/31157457/

 

DD: Epidermolytic acanthoma.

Agree, i suspect viral ethiology 

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HENRY

Posted

epidermolytic acanthoma 

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