Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2909 - 31 August 2021 Posted By: Saleem Taibjee

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

24F Punch biopsy right thigh, 2 year history of rash ?psoriasis


  Report Record

User Feedback


Krishnakumar subramanian

Posted

sub corneal pustule with basal cell vacuolar changes with some spongiosis and lymphocyte exocytosis.  A few necrotic keratinocytes are there in epidermis. I don't see eosinophils in dermis or vascular damage

could it be a drug rash/AGEP. It needs CPC

 

Share this comment


Link to comment
Share on other sites

Meenakshi Batrani

Posted

Could well be psoriasis or AGEP. But I would also do a DIF for IgA pemphigus where acantholysis may be inconspicuous leading to deceptive histology mimicking psoriasis. Would also do PAS to exclude Tinea. 

Share this comment


Link to comment
Share on other sites

I think i can see some fungi and spores,  i would do PAS first 

Share this comment


Link to comment
Share on other sites

Cem Leblebici

Posted

Need PAS to verify fungi. Agree with Volva.

Share this comment


Link to comment
Share on other sites

Saleem Taibjee

Posted

Yes, you guys are too good. Despite the unusual aspect of additional interface component to the inflammation in this recent case which I had not come across previously and I thought might throw you, this is indeed tinea. Please see PAS images below.

BW
Saleem

37007_20.0x PAS labelled.jpg

37007_40.0x PAS labelled.jpg37007_40.0x PASb labelled.jpg

Share this comment


Link to comment
Share on other sites



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...