Case Number : Case 2992 - 24 December 2021 Posted By: Dr. Richard Carr

Cyst wall contains cells with coarse keratohyaline granules and koilocytes. I think that this is a verrucous cyst.

On 24/12/2021 at 13:45, Anil Patki said:

Cyst wall contains cells with coarse keratohyaline granules and koilocytes. I think that this is a verrucous cyst.

Agree.  Cytopathc changes not as marked as Richard Carr's previous example:  Case 2104  29th June 2018

verrucous cyst

Agree with verrucous cyst. 

Thanks all. Agree with verrucous cyst, rather hybrid infundibular-tricholemmal. p53 and Ki67 are concordant peripheral patterns as expected in benign or reactive lesions. p16 show a low mosaic pattern which is probably normal for the sun-protected location deep in the dermis. The epidermal changes here reminded me of dermatofibroma but I was unconvinced by a dermal component suggestive of the latter.  Seasonal greetings and best wishes for the year to come. 

Thanks a lot, Richard, for your very educative and useful tips. Happy new year.