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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2739 - 5 January 2021 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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50 year old male with perianal lesion.


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vincenzo

Posted

Difficult! ? dAIN-associated micro invasive scc ( with some adenoid cystic change ). 

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Richard Logan

Posted

Pemphigus vegetans.

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I would be interested in PAS

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Alex-Ventura-Leon

Posted

Pemphigus vegetans is also my opinion. Although, i dont know what does image 5 try to show us.

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Uma Sundram

Posted

Localized pemphigus vegetans. DIF was positive. Patient with long history of vegetative lesions in intertriginous areas. What do you all think of image 5? Any ideas?

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Alex-Ventura-Leon

Posted

3 hours ago, Uma Sundram said:

Localized pemphigus vegetans. DIF was positive. Patient with long history of vegetative lesions in intertriginous areas. What do you all think of image 5? Any ideas?

It reminds me what we see in other organs (specially breast) and its called collagenous spherulosis

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Dr. Richard Carr

Posted

I'd guess it was a reactive cross cut follicle or maybe a perianal duct.

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