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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2750 - 20 January 2021 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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15 year-old female with left foot tumor.


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Alex-Ventura-Leon

Posted

Nodular Cystic Hidradenoma. There are some atypical features (bad delimitation and some infiltratives areas). But it seems total excised.

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Two-cell type seen forming ducts and there are some solid and cystic regions. Stroma is myxohyaline. Second benign mixed tumour of skin.

Further observation: luminal lining shows apocrine changes, hobnail with abundant eosinophilic cytoplasm

Wonder how to differentiate in this case between apocrine cystadenoma and digital papillary adenocarcinoma, agree that those should be considered too.

Looking forward to the answer.

 

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Meenakshi Batrani

Posted

I would consider apocrine cystadenoma and low grade digital papillary adenocarcinoma. the distinction between the two on digits can be challenging- see reference below: 

 

Molina-Ruiz AM, Llamas-Velasco M, Rütten A, Cerroni L, Requena L. "Apocrine Hidrocystoma and Cystadenoma"-like Tumor of the Digits or Toes: A Potential Diagnostic Pitfall of Digital Papillary Adenocarcinoma. Am J Surg Pathol. 2016 Mar;40(3):410-8. doi: 10.1097/PAS.0000000000000547

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Dr. Hafeez Diwan

Posted

Given the location and the papillary features, I called this digital papillary adenocarcinoma.

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