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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2756 - 28 January 2021 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Richard Logan

Posted

HPV infection. 

Most likely one of the HPV types associated with common flat warts such as HPV3. 

I have noticed that this is often called epidermodysplasia verruciformis (EDV) by pathologists.  This is confusing, because clinicians would only use the term EDV for very rare cases of a genetically inherited predispostion to widespread flat warts associated with a wide variety of rare HPV types.

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Carmen Lisievici

Posted

I will admit that I would call this epidermodysplasia verruciformis, but if the clinician describes it as an isolated lesion, than I would probably call it "EV acanthoma", as suggested in Mckee's pathology of the skin.

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Richard Logan

Posted

That makes more sense.

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Dr. Mona Abdel-Halim

Posted

This was typical case of epidermodysplasia verruciformis

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Richard Logan

Posted

Mona, by "typical" do you actually mean a case of the very rare genodermatosis epidermodysplasia verruciformis (EDV), or was this a common, plane wart in an otherwise normal patient?  Histologically of course the lesions look the same, but the implications of labelling a patient with EDV are significant.

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Dr. Mona Abdel-Halim

Posted

Dear Dr Richard

This was a male 27 who had generalized TV-like and plane wart like lesions progressively developing since childhood. His presentation fits with the genodermatosis EDV.

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