Case Number : Case 2887 - 30 July 2021 Posted By: Dr. Richard Carr

A difficult regressed melanocytic lesion...probably melanoma. It’s asymmetric. 

Are the figures 7th and 8th of the same case? What r the labeling of the immunos?

I wanted you to guess the IHC but the left two are p16 and the right two are melanA. Yes all images are the same case but agree that's important to check!

Images 7th and 8th and IHC were posted later but with only one comment at that point it sort of defeats the idea a little.

Sorry. I’m late. Fastweb has been out of order for two days in my town. 
how about a melanoma in situ overimposed in a BCC? Prognostically not too much dangerous? 

Superficial BCC with and regressed melanocytic lesion.

Superficial BCC colonised by melanocytes(denderitic) adjacent to melanoma in regression..

We concluded a pigmented BCC with regression could easily and more likely account for the pattern of superficial tumoural melanosis rather than a BCC and a regressed superficial melanoma. This would be Occam's razor solution i.e. keep it simple: 

Forgot to say thank you to Dr Domenico Mesiano for sharing this case. 

Gorgeous..And logic.. Thank u for this teaching case..

Thank you Richard and Domenico.