Case Number : Case 2858 - 21 June 2021 Posted By: Dr. Mona Abdel-Halim

Looks like a myopericytoma.

agree withy myopericytoma

Agree. 

There is lot of overlap between angioleiomyoma and myopericytoma which are considered a part of spectrum. In this case some smooth muscle bundles in between the vessels, and patchy Desmin positivity, may be favors angioleiomyoma over myopericytoma. 

2 hours ago, Meenakshi Batrani said:

There is lot of overlap between angioleiomyoma and myopericytoma which are considered a part of spectrum. In this case some smooth muscle bundles in between the vessels, and patchy Desmin positivity, may be favors angioleiomyoma over myopericytoma. 

Agree

Thank you all!

I found the prominent concentric arrangement of the short spindled ovoid cells around the blood vessels (onion peel pattern) together with the focal (rather than diffuse desmin staining pattern) more in keeping with the classic description of myopericytoma. A classic angioleiomyoma will have a less prominent concentric arrangement of the tumor cells around the blo0d vessels and a diffuse desmin positivity. But as Meenakshi said, in recent years the term myopericytoma is used to describe a spectrum of tumors that also includes angioleiomyoma and myofibroma. Whatever you prefer to call it, it is benign and no harm is expected to the patient! 

16 hours ago, Dr. Mona Abdel-Halim said:

Thank you all!

I found the prominent concentric arrangement of the short spindled ovoid cells around the blood vessels (onion peel pattern) together with the focal (rather than diffuse desmin staining pattern) more in keeping with the classic description of myopericytoma. A classic angioleiomyoma will have a less prominent concentric arrangement of the tumor cells around the blo0d vessels and a diffuse desmin positivity. But as Meenakshi said, in recent years the term myopericytoma is used to describe a spectrum of tumors that also includes angioleiomyoma and myofibroma. Whatever you prefer to call it, it is benign and no harm is expected to the patient! 

Agree.