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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2778 - 1 March 2021 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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RT cheek - C&C - 6mmx4mm wart lesion increase in size ?irritated seb keratosis exclude SCC


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Alex-Ventura-Leon

Posted

Same case as 2775 (24 february)

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Richard Logan

Posted

6 hours ago, Alex-Ventura-Leon said:

Same case as 2775 (24 february)

Yes, although the exposure is much better this time.  Iskander - what's the verdict on this one?

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Victor Delgado

Posted

Sebaceoma

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Dr. Mona Abdel-Halim

Posted

I will call it seb carc

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Josie Bisi

Posted

The lesion has expansive growth and, despite the mitotic activity, the cells are monomorphic. I get the diagnosis of Sebaceoma.

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Victor Delgado

Posted

Sebaceoma

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Admin_Dermpath

Posted

Yes, interesting discussion. This is a sebaecous tumour and the question is sebaceoma versus well diff seb carcinoma. I accept porocarcinoma is in the differential but I felt there was definite sebaceous differentiation. You can see increase mitotic activity in a sebaceoma, however, this is typically spare. Stigmata for carcinoma are prominent nucleoli, mitotically activity and pleomorphism - necrosis is a helpful feature. Deep extension, adnexal or lymphovascular invasion are all seen in carcinoma. 

This was reported as favouring an extra-ocular well differentiated sebeacous carcinoma. 

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