Case Number : Case 2786- 11 March 2021 Posted By: Saleem Taibjee

Carcinoma adnexal skin tumor or metastatic adenocarcinoma .

Thinking of Porocarcinoma...after ruling out any kind of mts of course!

Unfortunately the full set of images has not been provided. Hence attaching the others now.

Primary cutaneous cribriform (apocrine) carcinoma vs. primary cutaneous adenoid cystic carcinoma.

Yes! Primary Cutaneous Cribriform Carcinoma. 

Agree with above. Primary Cutaneous Cribriform Carcinoma.

Agree with primary cutaneous cribriform carcinoma

yes, agree  with  cutaneous cribriform apocrine carcinoma, but duration and the lung lesion is it biopsy proven sarcoid is needed sir

Metastatic ca must be excluded.. 

Yes, well done, this is primary cutaneous cribriform apocrine carcinoma. This is a recent case which came to me in routine sign out. It is the first such case I have personally seen, so I think it must be rather uncommon. But the histology is so distinctive, and remarkably similar to this publication: Rutten A, et al. J Am Acad Dermatol 2009;61:644-51. The patient also seems to fit into the correct dermographic group.

I did request some immunos, but not really convinced that these took me much further forward. CK7, in particular, was positive (shown below).

I must admit that the histology looked so typical that I don't think this is a metastasis.

BW
Saleem

Beautiful!

Astonishing!!! It was my pleasure to meet u!!!

Lovely case and agree it doesn't look like the usual metastasis.