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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2938 - 11 October 2021 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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F 56 ,Past history of right breast cancer in 2015 treated by lumpectomy, chemotherapy and radiotherapy, and she is now maintained on hormonal treatment. The patient noted recent development of a small vascular looking papule on the right breast.


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Meenakshi Batrani

Posted

Post radiotherapy related benign lymphangiomatous papules of the skin (BLAPs), or atypical vascular lesion. Don't see atypia for post radiation angiosarcoma. 

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31 minutes ago, msofopoulos said:

I have been taught that post-irradiation angioSa can be pretty subtle. MYC amplification should be checked. https://pubmed.ncbi.nlm.nih.gov/21909081/

i agree, was worried about angiosarc as well

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Eman El-Nabarawy

Posted

On 11/10/2021 at 07:51, Meenakshi Batrani said:

Post radiotherapy related benign lymphangiomatous papules of the skin (BLAPs), or atypical vascular lesion. Don't see atypia for post radiation angiosarcoma. 

Agree.

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vincenzo

Posted

I don’t see atypia, but there are many promontory signs and it seems ( not sure ) some dissecans pattern at the periphery of slide. What do you guys think about?

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Dr. Mona Abdel-Halim

Posted

C-MYC was negative

HHV-8 was negative

This was diagnosed as Atypical Vascular Lesion of radiotherapy (AVL)

 

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