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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2950 - 27 October 2021 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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34 year-old female with diabetes and chronic kidney disease, with tense bullae on right forearm and knuckles of left hand.


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daniellindsay

Posted

?Bullosis diabeticorum

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Anil Patki

Posted

Subepidermal cleft with eosinophils. Cell-rich bullous pemphigoid is the first possibility. Gliptin-induced pemphigoid is a newly emerging disorder in diabetics, which is a second possibility.

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Krishnakumar subramanian

Posted

sub epidermal bulla with eosinophils. could be drug induced BP or BP immune mediated. What is the blue color, is it mucin staining. if there is mucin in a bulla in the knuckle must we exclude dermatomyositis ?

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vincenzo

Posted

Cell-poor blister, basal lamina duplication, copious amounts of mucin..make me think of Dermatomyositis. 

 

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On 27/10/2021 at 14:10, Anil Patki said:

Subepidermal cleft with eosinophils. Cell-rich bullous pemphigoid is the first possibility. Gliptin-induced pemphigoid is a newly emerging disorder in diabetics, which is a second possibility.

I thought subepidermal blister with eosinophils and in that age more drug related i would think

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Dr. Hafeez Diwan

Posted

Bullous diabeticorum. Immunofluorescence studies were negative.

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