Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2951 - 28 October 2021 Posted By: Saleem Taibjee

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

78M, History of bladder ca. Several months of blistering of dorsum of hands, 3cm erythematous plaques with blisters & vesicles ?erythema elevatum diutinum ?Sweet syndrome ?PG


  • Like 2
  Report Record

User Feedback


Anil Patki

Posted

Neutrophilic dermatosis of dorsal hands. Dense neutrophilic dermal infiltrate with leucocytoclasia and vasculitis are the salient features. This is considered to be a localized variant of Sweet syndrome.

Share this comment


Link to comment
Share on other sites

Meenakshi Batrani

Posted

Agree with neutrophilic dermatosis of dorsal hands

Share this comment


Link to comment
Share on other sites

Krishnakumar subramanian

Posted

I agree it as a neutrophilic dermatosis

can it be related to Bacillus Calmette-Guérin therapy which is given for bladder cancer- some thing like drug related sweet syndrome. 

Share this comment


Link to comment
Share on other sites

Victor Delgado

Posted

Woooo... nice case. Tks for sharing

Share this comment


Link to comment
Share on other sites

vincenzo

Posted

Agree with a neutrophilic dermatosis of dorsal hands, because of topography and neutrophilic infiltrate, but not sure about pathologic chapter of NDDH. In last picture I see a concentric lamellar onion skin fibrosis...why not an early stage ( of a new bulls entry ) of EED?

Share this comment


Link to comment
Share on other sites

Saleem Taibjee

Posted

Thanks for the comments. I thought this was a nice recent example of neutrophilic dermatosis of the (dorsal) hands. This is a neutrophilic dermatosis on the spectrum of Sweet's, with a number of reported associations including malignancy, haematological disease and connective tissue diseases. As Krishnakumar mentions, drugs are sometimes implicated in Sweet's, but I am not certain for this case.

This case is also interesting because of a degree of epidermal and infundibular hyperplasia. There is some endothelial swelling which I highlighted, but I did not think there was genuine vasculitis, especially when one considers the density of the infiltrate. There are 2 schools: Either a) vasculitis is present, or b) is not present, in Sweet's. I am more in the second camp, but up for debate!

BW, Saleem

Share this comment


Link to comment
Share on other sites



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...