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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3069 - 12 April 2022 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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11 year old female with lesion on cheek.


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Shawn

Posted

Dusty cytoplasm, fascicular growth, bland cytology, no mitotic activity. favor DPN, would use beta-catenin for confirmation.

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Mohamed khaled

Posted (edited)

DPN

Edited by Mohamed khaled

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Mohamed khaled

Posted

24 minutes ago, Shawn said:

Dusty cytoplasm, fascicular growth, bland cytology, no mitotic activity. favor DPN, would use beta-catenin for confirmation.

Concur

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Chirag Desai

Posted

9 hours ago, Mohamed khaled said:

DPN

Can it have multinucleated giant cells? 

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Chirag Desai

Posted

Can DPN have multinucleated giant cells? Sorry for my ignorance; have just seen one case in the past

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Mohamed khaled

Posted

8 hours ago, Chirag Desai said:

Can DPN have multinucleated giant cells? Sorry for my ignorance; have just seen one case in the past

Although it is not common finding, multinucleated cells are reported in DPN 

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Uma Sundram

Posted

DPN. Beta catenin is positive.

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Uma Sundram

Posted

Deep penetrating nevus.

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Chirag Desai

Posted

13 hours ago, Mohamed khaled said:

Although it is not common finding, multinucleated cells are reported in DPN 

thanks

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Chirag Desai

Posted

10 hours ago, Uma Sundram said:

Deep penetrating nevus.

how do we differentiate this lesion from cellular blue nevus?

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Shawn

Posted

13 hours ago, Chirag Desai said:

how do we differentiate this lesion from cellular blue nevus?

Cellular blue nevus: look for adjacent common blue nevus component, lacks nuclear beta-catenin staining, less dusty cytoplasm.

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Chirag Desai

Posted

7 hours ago, Shawn said:

Cellular blue nevus: look for adjacent common blue nevus component, lacks nuclear beta-catenin staining, less dusty cytoplasm.

Ok, Thanks a lot for the explanation. 

 

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