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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 4152 - 20 December 2022 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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66 F, Punch biopsy mid back. Nodular mycosis fungoides
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Go to records December 2022

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R.Agrawal

Tumour stage MF with large cell transformation?

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Meenakshi Batrani

Meenakshi Batrani 0

Posted

Large cell transformation in the clinical setting of MF. In the absence of classic clinical setting of MF, then needs to be differentiated from other high grade T-cell such as ALCL and B-cell lymphomas on IHC. 

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Joy

Tumour stage mycosis fungoides with large cell transformation (greater than 25% and microscopic nodules). Blast-like appearance (never understood the 4 x diameter of small lymphocyte as this is mega large).  CD30 positivity would be of interest (usually CD30+).  Need compatible clinical history for mycosis fungoides.  

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Rathi

Nodular and wedge shaped

C-ALCL vs systemic to skin (LyP, type C)?

If p/h/o MF then Sezary/MF transformation if clinical fits

 

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