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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3017 - 28 January 2022 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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L forearm excision 15mm nodule ?keratoacanthoma exclude melanoma


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Admin_Dermpath

Posted

Dear all thank you for your comments.

The clinical concern and architecture is not of a classic pilomatrixoma - any other suggestions? Iskander

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Meenakshi Batrani

Posted

In view of significant mantle of basaloid cells One can consider proliferative pilomatricoma or matricoma or a panfolliculoma. All have overlapping features, tough to choose one between these based on images. 

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Admin_Dermpath

Posted

yes it’s the architecture and expansion and we called it a proliferating pilomatrixoma.

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Admin_Dermpath

Posted

Dear All Please find the description on this case. I showed a few colleagues:

Skin with a pilomatrical tumour showing nodularity and extension into deep dermis and fat. The baslaoid tumour cellls show no anaplasia and whilst mitoses are seen they are not atypical. No central necrosis is seen or lympho-vascular invasion.

The features are those of a proliferating pilomatrical tumour ((calcifying epithelioma of Malherbe).There is no evidence of malignancy, however, the nosological behaviour of these intermediate lesions is not clearly defined and clinical follow up is advised

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