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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3053 - 21 March 2022 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
M 27 Oral lesions
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Go to records March 2022

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Shawn

Intraepidermal acantholysis, not a clean suprabasal cleft. Things to exclude: HSV, mucosal Grover's and Pemphigus (vulgaris); Need clinical and immunofluorescence data. 

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Meenakshi Batrani

Meenakshi Batrani 0

Posted

I am favoring pemphigus vulgaris. However definitive diagnosis is subject to clinical correlation and DIF.  How common or uncommon is mucosal involvement in Grover's disease, not aware of mucosal Grover's disease. 

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Shawn
7 hours ago, Meenakshi Batrani said:

I am favoring pemphigus vulgaris. However definitive diagnosis is subject to clinical correlation and DIF.  How common or uncommon is mucosal involvement in Grover's disease, not aware of mucosal Grover's disease. 

Rare - like case report rare.

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msofopoulos

msofopoulos 4

Posted

Suprabasal cleft with lots of neutrophils and few eosinophils. I see only one histologic pattern (suprabasal acantholysis) but no corp ronds nor grain formation. I favour P Vulgaris.

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