Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3053 - 21 March 2022 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

M 27 Oral lesions


  Report Record

User Feedback


Shawn

Posted

Intraepidermal acantholysis, not a clean suprabasal cleft. Things to exclude: HSV, mucosal Grover's and Pemphigus (vulgaris); Need clinical and immunofluorescence data. 

Share this comment


Link to comment
share_externally

Meenakshi Batrani

Posted

I am favoring pemphigus vulgaris. However definitive diagnosis is subject to clinical correlation and DIF.  How common or uncommon is mucosal involvement in Grover's disease, not aware of mucosal Grover's disease. 

Share this comment


Link to comment
share_externally

Shawn

Posted

7 hours ago, Meenakshi Batrani said:

I am favoring pemphigus vulgaris. However definitive diagnosis is subject to clinical correlation and DIF.  How common or uncommon is mucosal involvement in Grover's disease, not aware of mucosal Grover's disease. 

Rare - like case report rare.

Share this comment


Link to comment
share_externally

msofopoulos

Posted

Suprabasal cleft with lots of neutrophils and few eosinophils. I see only one histologic pattern (suprabasal acantholysis) but no corp ronds nor grain formation. I favour P Vulgaris.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...