Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3059 - 29 March 2022 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

73 year old female with history of breast carcinoma, now with new eyelid lesion.


  • Thanks 1
  Report Record

User Feedback


Shawn

Posted

Infiltrating atypical cells with CK reactivity, would confirm with GATA3/ER/CK7

Share this comment


Link to comment
share_externally

Meenakshi Batrani

Posted

Metastasis most likely. 

Share this comment


Link to comment
share_externally

vincenzo

Posted

Histiocytoid ( signet ring cell ) Carcinoma of the eyelids. p63/GATA3, but overall CPC, to rule out mets breast ILC. 

Share this comment


Link to comment
share_externally

msofopoulos

Posted

On 31/03/2022 at 15:46, vincenzo said:

Histiocytoid ( signet ring cell ) Carcinoma of the eyelids. p63/GATA3, but overall CPC, to rule out mets breast ILC. 

Agree! Monocle tumors are quite rare and look alot like lobular Ca but they are E--Cadherin positive. We should rule out ILC first (what was the histology of the breast ca?)

 

Share this comment


Link to comment
share_externally

Uma Sundram

Posted

The patient had a lesion of metastatic breast carcinoma on this location, and this is a recurrence. CK7+gata+. Easy to miss-there were only about 8 cells in total. Reminder that ILC can be quite subtle in an unusual location.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...