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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 3096 - 16 May 2022 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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"M 23, The patient has dystrophic epidermolysis bullosa. He presented with a rapidly progressive ulcer on the dorsum of the right foot/lower leg with necrotic floor showing protuberant exophytic nodular growths for 7 months duration. In addition, multiple nodules are seen in the skin surrounding the ulcer as well as on the shin of tibia away from the ulcer."


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Anil Patki

Posted

Squamous cell carcinoma developing in the chronic ulcerative lesions of dystrophic epidermalysis bullosa.

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Meenakshi Batrani

Posted

1 hour ago, Anil Patki said:

Squamous cell carcinoma developing in the chronic ulcerative lesions of dystrophic epidermalysis bullosa.

Agree

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vincenzo

Posted

14 hours ago, Anil Patki said:

Squamous cell carcinoma developing in the chronic ulcerative lesions of dystrophic epidermalysis bullosa.

Yes, SCC, acantholytic pattern. 

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Krishnakumar subramanian

Posted

infiltrative type of SCC

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Dr. Mona Abdel-Halim

Posted

This was a grave case of invasive poorly differentiated SCC arising in a dystrophic EB patient.

It showed different types of SCC: acantholytic, pseudo-vascular, and infiltrative.

At time of diagnosis, the patient was already having widespread metastasis and unfortunately, he died. 

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