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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 4002 - 24 May 2022 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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78 year old male with lesion on the umbilicus.


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Anil Patki

Posted (edited)

Sister Joseph nodule. Metastasis from GIT malignancy. Epidermotropic metastasis, could be from a prostatic carcinoma.

Edited by Anil Patki
Addendum

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Meenakshi Batrani

Posted

Yes. Metastasis

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vincenzo

Posted

Melanoma. 

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Eman El-Nabarawy

Posted

Melanoma.

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vincenzo

Posted

Cannot seen real nests, but when I see cells pushing against each other, first thought is Melanoma. 

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msofopoulos

Posted

At first glance i thought it was a melanoma with lots of emboli, but I think i see intracellular mucin, so its probably a metastasis and this location is a known spot for GI mets. Would like to do an alcian blue and a brown stain to rule out melanoma

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Uma Sundram

Posted

This is an amazing case of a sister Mary Joseph nodule of someone with a lung primary. TTF1 is positive and melanoma markers are negative.

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vincenzo

Posted

wuahoo! Very great case. Thanks Uma. 

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