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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : CASE 4401 - 04 December 2023 Posted By: Admin_Dermpath

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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A 53-year-old, African American lady presented with a painful lesion on the left thumb and quickly progressed to many new lesions on her left breast, right nostril, right suprapubic region, left heel and left calf within 18 months, clinical differential diagnoses were spongiotic dermatitis, lymphoproliferative disorder or others.

What is the best diagnosis?
a) Mycoses Fungoides.
b) Primary cutaneous gamma-delta T cell lymphoma.
c) Primary cutaneous CD4 positive small/medium sized T cell lymphoma.
d) Dermal hypersensitivity reaction.
e) Pityriasis lichenoides et varioliformis acuta.


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smbaksh@psppath.com

Posted

Cytotoxic phenotype with no significant betaF1 positivity in the epidermotropic component- agree with primary cutaneous gamma-delta T-cell lymphoma.

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10 hours ago, smbaksh@psppath.com said:

Cytotoxic phenotype with no significant betaF1 positivity in the epidermotropic component- agree with primary cutaneous gamma-delta T-cell lymphoma.

Totally agree with this comment

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Admin_Dermpath

Posted

Many thanks everyone for your comments. The final diagnosis is: Primary cutaneous gamma-delta T-cell lymphoma

Best wishes

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