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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 4189 - 09 February 2023 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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82 M Right earlobe 4mm punch biopsy
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Go to records February 2023

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Anil Patki

Anil Patki 4

Posted

Infiltrate of atypical lymphoid cells with epidermotropism requires IHC and search for any systemic lymphoma. Could be a primary cutaneous aggressive epidermotropic T cell lymphoma

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Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Favor melanoma.. Of course immunos will solve the issue..

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Atreyo Chakraborty

Atreyo Chakraborty 0

Posted

I also favor more a Lymphoma especially B Cell types, specifically PCFCL, think there is a vague tendency for follicle formation especially in the 2nd set of images. In the 2nd set, epidermis seems to be spared. A word of caution: reactive phenomenon often mimics neoplastic processes especially with Lymphomas - so IHC is compulsory to differentiated between a benign reactive process (Eg: Pseudolymphomas) vs true lymphomas

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Iskander H. Chaudhry

Iskander H. Chaudhry 49

Posted

Thank you for your comments. This is a nodular mycosis fungoides with CD4 staining and showing areas of transformation.

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