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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : CASE 4276 - 12 June 2023 Posted By: Dr. Mona Abdel-Halim

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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F, 47 Multiple indurated subcutaneous nodules and plaques on the extremities.


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Meenakshi Batrani

Posted

Lymphocytic lobular panniculitis with rimming of adipocytes.  SPTCL, although, distinction from lupus panniculitis requires IHC.

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SPTCL, with classical atypical lymphocytes ( they should be beta-F1+, CD8+, and TIM3+, a new entry in IHC panel ), rimming adipocytes. But I'm seeing HLH, also, or am I wrong? HLH could be an adversal prognostic sign. 

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Lobular panniculitis, atypical looking Lc rimming adipocytes, HLH i also can see. My first differential is SPTCL , needs immuno

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Eman El-Nabarawy

Posted

On 28/06/2023 at 09:53, Meenakshi Batrani said:

Lymphocytic lobular panniculitis with rimming of adipocytes.  SPTCL, although, distinction from lupus panniculitis requires IHC.

With bean bag cells!

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Dr. Mona Abdel-Halim

Posted

Yes, this was SPTCL 

 

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