Case Number : CASE 4221 - 27 March 2023 Posted By: Dr. Mona Abdel-Halim

Will need immunophenotyping. Looking at the large cells and the fact that it's a recurrent eruption, lymphomatoid papulosis comes to my mind.

Rosai-Dorfman disease?

On 04/05/2023 at 07:27, Anil Patki said:

Will need immunophenotyping. Looking at the large cells and the fact that it's a recurrent eruption, lymphomatoid papulosis comes to my mind.

Agree..

Likely Lymphocytes - Pleomorphic vesicular nuclei present. Could be Lymphomatoid papulosis.....

On 04/05/2023 at 20:23, R.Agrawal said:

Rosai-Dorfman disease?

This is NOT a lymph node biopsy. The other name for Rosai Dorfman is "Sinus Histiocytosis with massive Lymphadenopathy". It has very rare cutaneous manifestations. So that is an unlikely diagnoses here, in my opinion

Lymphomatoid Papulosis, type C ( hallmark cells in last pic ). Primary Cutaneous ALCL contains semicohesive strands and nests of anaplastic cells, instead the anaplastic cells are isolated and scattered, here. 

Yes, this was LyP. CD30 was positive