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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : CASE 4478 - 20 March 2024 Posted By: Admin_Dermpath

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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64-year-old woman. Erythematous and infiltrated papular lesions Trunk, upper and lower limbs, For one year
Contributor: Pr. Béatrice VERGIER
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Go to records March 2024

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Anil Patki

Anil Patki 4

Posted

Psoriasiform lichenoid reaction pattern with epidermotropism. MF is the most likely diagnosis to be confirmed by IHC

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Meenakshi Batrani

Meenakshi Batrani 0

Posted

Papular MF or pityriasis lichenoides which can have significant epidermotropism simulating MF. Clinical history of lesions resolving on its own and IHC will help. 

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Admin_Dermpath

Admin_Dermpath 1,211

Posted

Thank you for your comments. 

The final diagnosis is: Type D lymphomatoid papulosis

The differential diagnoses to consider are:

Mycosis Fungoides
Type B lymphomatoid papulosis
Pityriasis lichenoides
Drug eruption
 

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vincenzo

vincenzo 4

Posted

Not sure about MF,because the intraepidermal lymphcytes aren't larger than intradermal ones

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Admin_Dermpath

Admin_Dermpath 1,211

Posted

I have uploaded the immunochemistry of this case also.

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vincenzo

vincenzo 4

Posted

Very interesting case, thanks so much. 

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msofopoulos

msofopoulos 4

Posted

the duration of the lesion (1 year) make me also think towards MF. (i think lymphomatoid papulosis does not last that long, it comes and goes)

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