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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : CASE 4601 - 06 March 2025 Posted By: Admin_Dermpath

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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74-year-old female with erythematous papules and plaques with scale on bilateral upper and lower extremities. History of small cell lung cancer on immunotherapy. R/O MF.
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Jacob

Jacob 0

Posted

Agree with psoriasis

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Cem Leblebici

Cem Leblebici 1

Posted

Psoriasis. Propably immunotherapy-related.

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Dr. Shoba Ramesh

Dr. Shoba Ramesh 0

Posted

Immunotherapy (Pembrolizumab induced) lichenoid drug eruption 

hyperkeratosis, parakeratosis, scattered apoptosis, basal layer vacoulation,  

near to saw toothed rete, upper dermal edema with eosinophils, dense lichenoid reaction pattern,

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Tausif Saleem

Tausif Saleem 0

Posted

Psoriasis. 

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Adelina-Maria Cohn

Adelina-Maria Cohn 0

Posted

Immunotherapy induced psoriasis

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vincenzo

vincenzo 4

Posted

Agree with psoriasis. 

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msofopoulos

msofopoulos 4

Posted

looks like psoriasis. the eos are part of the psoriasis?

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smbaksh@psppath.com

smbaksh@psppath.com 0

Posted

Diagnosis: Pembrolizumab-induced psoriasiform dermatitis.

The eosinophils indicate that this eruption is drug-induced. 

Thank you for viewing this case.

 

Suzuki M, Matsumoto S, Takeda Y, Sugiyama H. Systemic Psoriasiform Dermatitis Appeared after the Administration of Pembrolizumab. Intern Med. 2020 Mar 15;59(6):871-872. doi: 10.2169/internalmedicine.3694-19. Epub 2019 Nov 29. PMID: 31787697; PMCID: PMC7118380.

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