In this section we have Logan's cases since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.

Baso-squamous BCC/collision tumour with clear-cell variant of AFX.

By Operations Pathhub

May 29

Followers 0

Case 1007 2.5.14 (R. Carr) M 75 ?BCC scalp

Difficult case. At first glance looked like sebaceous or liposarcoma with malignant-looking clear cells. These were actually CD68+ve AFX variant. 30% of the specimen composed of epithelial component squamoid BCC (Ber-EP4+ve).

Message: sebocyte-like differentiation isn’t always true sebaceous differentiation.

DD: clear-cell melanoma – no answer re melanocyte markers