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In this section we have Logan's cases since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.

Blastic dendritic plasmacytoid lymphoma (BPDCN)


Operations Pathhub

Case 581  30.8.12 (P. Mckee)  M 48 tumour on back. 

Very difficult diagnosis. The tumour is believed to be derived from precursors of plasmacytoid dendritic cells and is included within the acute myeloid leukemia spectrum. The tumour cells express CD4, CD43, CD56 and less consistently CD68, CD123, CD305 and TCL1 may also be expressed. The infiltrate consists of a monotonous infiltrate of medium sized blast cells.  Most cases present in skin but quickly become leukaemic. 

 

Case 1931  24.10.17  (A Bakshi)  chest swelling 

Dense B-cell pattern nodular infiltrate.  Cells have a plasmacytoid morphology. 

IH: +ve for CD4, 56, 123 

 

Case 2450   22.11.19  (R. Carr)  M 72 scalp 

B-cell lymphoma pattern, but CD20 –ve,  CD 4 +ve; CD56 +ve; CD123 +ve  New drug tagraxofusp targets CD123 


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