Case 315 Aug 11 (P. McKee) M middle aged. Inguinal node
Benign tumour of smooth muscle cells and myofibroblasts. Amianthoid collagen fibres. Usually shows SMA +ve globules and cyclinD-1 ++. Associated with HHV8 and EBV. Extravasated RBC’s are common and cause confusion with KS.
DD: neurilemmoma; also looked like fibromyxoid sarcoma with herring-bone pattern.
Case 1143 10.11.14 (IH Chaudhry) M 49 enlarging groin lesion (typical presentation)
Very rare. Lymph node replaced by spindle cell tumour compressing remainder of node to edge into a collagenous pseudocapsule. Bland spindle cells showing Antoni-A pattern of nuclear palisading. Intraparenchymal haemorrhage and haemosiderin. Amianthoid bodies – collagen fibres with dark eosinophilic centre and paler stellate periphery. Fuchsinophilic material red on Trichrome stain.
IH: spindle cells +ve vimentin, SMA and cyclin D1. Ki-67 low.
Ref: Nguyen T. Arch Path Lad Med 2007; 131(2): 306-10
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