Epithelioid haemangioendothelioma

Case 314  Aug 11 (IH Chaudhry)  M penile lesions 

Infiltrative tumour, composed of nests and cords of large epithelioid cells with abundant eosinophilic cytoplasm, vesicular nuclei, prominent nucleoli, and some nuclear pleomorphism.  CD31+++ 

Case 513   May 2012 (P. McKee)  F 35 ? pyogenic granuloma 

Differentiated from epithelioid angiomatous nodule because of abundant hyaline stroma in this condition. 

DD: Bacillary Angiomatosis – endothelial cells with watery cytoplasm, neutrophils and pseudoepitheliomatous hyperplasia 

Case 903  4.12.13  (H. Diwan)  F 48 wrist mass 

Opinion divided between this entity and angiosarcoma.  Both atypia and mitotic index low here.  Periphery of adult typical site.  This entity is intermediate in biology between haemangioma and angiosarcoma.  Usually CD31/34 +ve. 

Case 2497  31.1.20 (R. Carr)  F 70 below right clavicle (diagnosis disputed) 

Malignant vascular neoplasm with indolent behaviour.  Some thought could be angiosarcoma. 

Case 3004 11.1.22 (U. Sundram)  F 35 nodule on back 

Densely cellular dermal tumour with dissection of collagen suggesting malignancy.  Vessels with inconspicuous lumen and endothelial cells having plump, pale, banal-looking nuclei, and dense lymphoid infiltrate.  ERG +ve/HHV 8-ve. 

Case 4532  4.6.24 (J Costa Rosa) M 48 forearm nodule