Glomus tumour

Case 99 Oct 10 (P. McKee)  Rather uniform monotony of cells suggested poroma, but there is a suggestion of cells lining up in glomus fashion. 

Case 237   May 2011 (IH Chaudhry) (*teaching) 

Case 298   Aug 2011 (P. McKee)  M 32 painful nodule arm (*teaching) 

Beautiful teaching example 

Case 1229 10.3.15  (U. Sundram)  M 40 sub-ungual (*teaching) 

Classical – slides rather eosinophilic 

Case 1303   2.6.15 (M. Hurt)  M 53 arm 

Good close-up cytology of glomus cells: perinuclear vacuole; bubbly eosinophilic cytoplasm 

Case 1948  16.11.17  (IH Chaudhry)  F 65 toe ? pyogenic granuloma 

Not at all typical.  Very solid, lacking the normal double layer of cells or obvious vascularity, and rather epithelioid.  Some thought epithelioid DF. 

IH: +ve CD34 and SMA. -ve: S100, p63, EMA, Desmin and AE1AE3. 

Case 1965 11.12.17 (L. Yu) 33 sub-ungual 

Again not at all typical.  This one is biphasic with pale myxoid areas and darker cellular areas.  These presumably are the glomus cells (SMA +ve) but not typical. 

Case 2171 4.10.18  (R. Perret) M 30 acral 

Typical cytology with some mucinous change.  Strong +ve stain with h-Caldesmon (smooth muscle stain) 

DD Myoepithelioma 

Case 2658 14.9.20 (IH Chaudhry) M 62 forearm – previous lipoma excision (*teaching)  

Case 2945  20.10.21 (H. Diwan) M 38 elbow mass 

SMA +ve.  Unusual site for glomus, and a good case could be made for synovial metaplastic cyst with haemorrhage. 

Case 4008 1.6.22 (H. Diwan)  M 66 lesion upper arm 

Very heavily pigmented (presumably haemosiderin) 

Case 4175  20.1.23 (IH Chaudhury) M 56 lesion on thigh 

Case 4218  22.3.23 (H. Diwan) M 55 ?cyst, hand 

Case 4471  11.3.24 (M. Abdel-Halim) M 45 forearm nodule 

Case 4492 9.4.24 (U. Sundram) M 29 nail bed tumour 

Doesn’t show the classical cytology.