Hailey-Hailey disease

Case 1210 11.2.15 (H. Diwan)  F 64 back 

Very focal – some thought Grover’s. 

Case 1535  12.5.16 (H. Diwan)  M 39 eroded lesions axilla and groin (*teaching) 

Beautiful teaching histology 

Case 1927  18.10.17 (IH Chaudhry)  M 55 multiple itchy lesions, trunk and forearms 

I’m not sure this is the right diagnosis.  Full thickness epidermal necrosis with underlying vascular dilation.  Quite deep inflammatory change.  Acantholysis and dyskeratosis. There was a family history of H-H disease.  Perhaps a lot of secondary traumatic artefact. 

Case 2132  10.8.18  (R. Carr) Axillary biopsy  +ve family history (*teaching) 

Classical teaching histology. 

Case 4079 8.9.22 (S. Taibjee) F 34 7 year history of sore itchy areas on breasts, dev. blisters 

Initial levels showed only subtle, supra-basal clefting.  Deeper levels showed a more dramatic, acantholytic disorder with corps ronds and dyskeratosis.  No IF done.  Another example of “the best stain is a deeper section”. 

Case 4311  31.7.23 (M. Abdel-Halim) M 43 lesions in flexures 

Classical dilapidated brick wall, although could have been PV.