Grover’s disease

Case 859  2.10.13 (H. Diwan)  M  75 rash abdo.  Superficial acantholysis. 

Case 1134 28.10.14 (U. Sundram)  M 57 pruritic papules, chest (*teaching) 

Nice, rather subtle example 

Case 1376 1.10.15 (H. Diwan)  M 74 back 

Slides upside down 

Case 1563 22.6.16 (H. Diwan) F 74 back 

Would have done OK for pemphigus. 

Case 2141  23.8.18  (IH Chaudhry)  F  55 rash, abdo. 

Acantholysis with erosion, epidermal dysmaturation.  Some thought acantholytic Bowen’s but no solar elastosis. 

Case 2589 9.6.20  (U. Sundram)  F 50 new rash back 

Histology dominated by serous cap invaginating epidermis.  Few small foci of acantholysis with eos in infiltrate.  IF –ve.  Presence of eosinophils helps to distinguish Grover’s from Darier’s disease. 

Case 2741 7.1.21 (S. Taibjee) F 54 Behçet’s disease.  Punch biopsy chest 

Focal area of mild psoriasiform hyperplasia.  Acantholysis was minimal and extremely subtle.  A second biopsy showed it more obviously. 

Refs: Am J Dermatopathol 2010 32: 541-9.    Am J Dermatopathol 2010 32: 565-7. 

Case 2838  24.5.21  (M. Abdel-Halim) M 73 itchy papules, trunk, 6 months (*teaching) 

Classical both histologically and clinically 

Case 4163  3.1.23 (IH Chaudhry) M 86 itchy lichenoid papules on trunk 

Parakeratosis, psoriasiform hyperplasia, moderate spongiosis, vascular ectasia and neutrophilic debris.  Dysmature foci with keratinocyte atypia. No acantholysis. 

Case 4268  31.5.23 (H. Diwan) M 80 papular eruption